- #UNBEATABLE CHESS STRATEGY HOW TO#
- #UNBEATABLE CHESS STRATEGY SOFTWARE#
- #UNBEATABLE CHESS STRATEGY PROFESSIONAL#
#UNBEATABLE CHESS STRATEGY SOFTWARE#
A central component of the Interrogative Biology platform, bAIcis module, is a “state of the art Bayesian artificial intelligence learning software used for patient stratification, precision medicine, target identification, and lead optimization of novel drug candidates.” Later on, the company developed a sophisticated AI platform called Interrogative Biology. Owning unique proprietary data is gold in the era of artificial intelligence, so that was a strategic move.
Fast forwarding to the present day, the company has built one of the world’s largest biobanks of human specimens, with a large repository of molecular and clinically annotated phenotype data. Those included over 40 types of cancer cells - multiple types of breast cancer, prostate cancer, etc - along with healthy tissue extracted from the same patients. In 2009, Berg bought cancer tissue samples from more than 1,000 cancer patients at various medical schools from across the US. Founded in 2006, the company went a long way to building an impressive clinical portfolio. After all, Andreessen Horowitz himself and folks at SoftBank took the bet on the company in 2018, among other investors.įinally, my third pick in the 2016 article was Boston-based Berg Health. But who knows, things are definitely moving forward and I am curious what they will come up with this year. Well, to be fair, it seems a bit moderate for a 9-year-old AI-driven drug discovery company, in my opinion (in relative terms to some other industry players with similar R&D approaches). TwoXAR (Aria Pharmaceuticals) now has a pipeline of a dozen preclinical candidates, around $15 million raised in total venture capital and recent positive in vivo results for one of their candidates for idiopathic pulmonary fibrosis (IPF). Atomwise is probably one of the most successful examples of using structure-based drug discovery strategy using deep learning, they have always maintained it super focused. Essentially, their algorithm keeps filling in a protein pocket of a digitally-encoded protein structure, atom by atom, until it comes up with a ligand optimal for modulating the protein - like searching for a perfect key to a lock. The three companies are approaching drug discovery in quite different ways:Ītomwise developed the AtomNet engine, based on a convolutional neural network (CNN), to run ultra-large virtual screening in chemical spaces of up to billions of synthesizable molecules against a known target of interest. The examples and exercises will improve your chess significantly and are suitable for any reader from club player to grandmaster level.Back in 2016, I wrote my first article about artificial intelligence in the pharmaceutical industry, ‘The Coming Boom In Drug Discovery.’ It featured several companies I got impressed by at the time: Toronto-based Atomwise (later moved to San Francisco), TwoXAR (later rebranded into Aria Pharmaceuticals), and Berg Health (acquired by BPGbio in 2023).
He has gathered a rich collection of strategic lessons he has been teaching worldwide, drawing mainly from his personal experience. 'Tivi' is famous for his deep chess knowledge and rock-solid positional play.
#UNBEATABLE CHESS STRATEGY HOW TO#
And one of the most challenging questions is: how to navigate different pawn structures? Sergei Tiviakov gives you all the answers in this first volume of his highly instructive series on chess strategy. Once you settle down for your game and the first moves have been played, you will need a deeper understanding of the middlegame. If chess players trust that their knowledge of opening theory and tactics is enough to survive in tournament play, they are mistaken. In his first book, he explains everything he knows about the fundament of chess strategy: pawn structures. He was born in Russia and trained in the famous Russian chess school.
Who better to teach you rock-solid chess strategy than Tiviakov.
#UNBEATABLE CHESS STRATEGY PROFESSIONAL#
Sergei Tiviakov was unbeaten for a consecutive 110 professional chess games as a grandmaster, a record that has only been broken by World Champion Magnus Carlsen.
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